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ThinkFeelDo is a web-based treatment for depression designed to extend treatment to those who may be unable to access traditional psychological interventions.

The ThinkFeelDo web application is based on the principles of cognitive behavioral therapy and is accessible via desktop and laptop computers as well as mobile devices. ThinkFeelDo provides information via interactive skill building exercises, text and video, and supports communication with a human coach via secure messaging. Coaches use an online dashboard to see a user’s activity on the site, allowing for targeted positive reinforcement, assistance and support.

Through our clinical trials, ThinkFeelDo has been tailored to meet the needs of diverse populations across the age spectrum, including adolescents, adults and older adults. Variations of ThinkFeelDo have also included social network platforms for users to engage in with one another to added social support. ThinkFeelDo has been shown to be effective for depression in general populations, as well as for youth and older adults.

The PI is David C. Mohr, PhD.

Project Names


  • R01 MH095753 (TeleHealth Study; PI Mohr)
  • P20 MH090318 (MoodTech and Project Tech Studies; PI Mohr)

Evaluation Groups

  • Adults (18+) with depression
  • Older adults (65+) with depression
  • Adolescents (14-18) with depressive symptoms


  • Mohr DC, Cuijpers P, Lehman K. Supportive Accountability: A Model for Providing Human Support to Enhance Adherence to eHealth Interventions. J Med Internet Res. 2011;13(1):e30.
  • Schueller SM, Tomasino KN, Mohr DC. Integrating Human Support into Behavioral Intervention Technologies: The Efficiency Model of Support. Clinical Psychology: Science and Practice. 2016(24):27-45.
  • Tomasino KN, Lattie EG, Ho J, Palac HL, Kaiser SM, Mohr DC. Harnessing Peer Support in an Online Intervention for Older Adults with Depression. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 2017;25(10):1109-1119
  • Lattie EG, Ho J, Sargent E, Tomasino, K.N., Smith, J.D., Brown, C.H., Mohr, D.C. Teens engaged in collaborative health: The feasibility and acceptability of an online skill-building intervention for adolescents at risk for depression. Internet Interventions. 2017;8:15-26.
  • Chen AT, Wu S, Tomasino KN, Lattie EG, Mohr DC. A multi-faceted approach to characterizing user behavior and experience in a digital mental health intervention. J Biomed Inform. 2019;94:103187.

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