Technology-enabled services (TESs), which use web-based and mobile applications for patients coupled with support from a care coordinator, have consistently been shown through randomized controlled trials to be effective at treating depression. However, attempts to implement TESs in healthcare settings have failed, primarily because neither real-world patients nor providers use the tools we develop and evaluate in research. This NIMH ALACRITY Center addresses the research-to-practice problem using our Accelerated Research-to-Sustainment (ACTS) framework. We will design and evaluate TESs for depression in three unique clinical settings that commonly manage depression. Each project integrates clinical psychology, human-computer interaction and implementation science across the design and evaluation phases. If you have questions, please contact us at 312-503-6585 or email us at cbits@northwestern.edu.